Precision to proteomics workflows.

A further expansion of Tecan's portfolio for specialist applications with the upcoming launch of Resolvex® i300 and its antibody purification columns, AffinEx™ Protein A Capture has been announced. The products deliver new levels of efficiency and precision to proteomics workflows, including biomarker discovery, drug development and personalized medicine research.

Proteomics laboratories have long struggled with tedious sample preparation, as well as the need to process large numbers of samples quickly and efficiently while minimizing the risk of cross-contamination.

The Resolvex i300, scheduled for launch in H1 2024, is a positive pressure module for solid phase extraction (SPE) and filtration, specifically designed to address all these challenges. Integrated into the Fluent® Automation Workstation, it enables the automation of every step of the sample purification process, including clean-up, evaporation and resuspension. This ensures the integrity and consistency of each sample while the instrument’s unique droplet-protection feature reduces the risk of cross-contamination during labware handling. Designed for use in various fields – including proteomics, genomics and analytical chemistry – the Resolvex i300 can easily be changed between 24- and 96-well labware formats and is particularly useful for liquid chromatography-mass spectrometry (LC-MS)-based applications.

Another exciting addition to Tecan’s portfolio for proteomics is the AffinEx™ Protein A Capture column. This novel antibody purification sorbent is stable, wet or dry, at room temperature, which significantly extends its shelf life and also reduces shipping costs. Available in a Narrow Bore Extraction™ (NBE™) format, AffinEx columns are ideally suited for use with the Resolvex i300, though they can be used with other automation platforms. The columns are specifically tailored to the biopharma industry and promise unparalleled efficiency for the isolation and purification of monoclonal antibodies.

Luca Valeggia, Senior Vice President of Lab Automation at Tecan, said: “Tecan has established a strong reputation in automating proteomics workflows. Resolvex i300 and AffinEx Protein A Capture are exciting additions to our portfolio, enabling us to address a broad range of customer needs, from low- to high-throughput, in both research and clinical settings. As demand for this challenging application grows, we are committed to continuous innovation that supports our customers in their efforts to understand the mechanisms of disease and develop reliable diagnostics and treatments for patients.”

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"The lab of the future is here!"

Digital tools to enhance lab productivity.

Two cutting-edge digital products – LabNavigator™ and Next-Gen Introspect™ – are to be introduced, by Tecan, at the SLAS2024 International Conference and Exhibition (3-7/2/2024-Boston MA USA) to improve the efficiency of laboratory operations. The new tools bring the transformative power of digitalization to laboratory operations, empowering researchers and lab technicians with the most advanced, user-friendly, integrated technologies.

The scale-up of laboratory research is often hindered by a lack of automation expertise and the complexity brought by disconnected workflows. As throughput increases, digitalization is crucial to overcoming these challenges by streamlining lab processes, as well as maximizing overall lab effectiveness and helping lab technicians to overcome skill barriers.

LabNavigator is a cloud-based, intuitive digital product that guides lab operators through end-to-end workflows using a single, straightforward interface. It builds an interconnected lab by seamlessly combining lab equipment – including Tecan liquid handling platforms and selected third-party devices – as part of an open digital ecosystem. LabNavigator creates easy-to-follow end-to-end workflows, enabling entry-level staff to effectively operate systems via a user-friendly interface that provides quick and easy onboarding. This not only multiplies the impact of experienced personnel, it increases the quality and reproducibility of lab processes. Overall, the ‘single pane of glass’ approach unifies heterogeneous automation systems to enable seamless scalability across multiple labs.

Tecan’s second digital product announcement is Next-Gen Introspect, which will be commercially released in Q2 2024. This state-of-the-art laboratory insights tool builds on Tecan’s well-established platform, Introspect. The next generation platform offers intuitive user experience, employing advanced data science to convert instrument and workflow data into actionable insights that will maximize the utilization, quality and performance of instrument fleets. Next-Gen Introspect unlocks service excellence by enabling remote diagnostics and service support, leading to higher instrument uptimes and fewer unplanned outages. The existing features focused on run success rates, consumables consumption and real-time monitoring, have been meticulously enhanced, helping lab managers to truly maximize their valuable resources. Both Next-Gen Introspect and LabNavigator are built on modern and secure back-end architectures, ensuring data and process security.

“The lab of the future is here,” said Dr Klaus Lun, Executive Vice President of Life Sciences Business Division at Tecan. “We have been empowering our customers to improve lab productivity through automation for over 40 years, and we are proud to champion the advantages of digitalization. With LabNavigator and Next-Gen Introspect, we can provide tangible results for our customers – reducing operator training needs, increasing run success rates, maximizing overall equipment and labor efficiencies, and providing data-driven actionable insights.”

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